Plasma Taurine (Taurine)
Sulfur-containing beta-amino acid synthesized from cysteine, acting as an essential organic osmolyte and antioxidant.
Standard vs. Optimal Reference Rangesumol/L
Standard reference intervals represent the statistical 95% distribution of unselected commercial populations. Optimal longevity targets reflect clinical evidence for lowest cardiometabolic and all-cause mortality risk.
Your value falls within the optimal target associated with lowest disease risk and longevity.
35 - 120 umol/L
General reference distribution across unselected commercial populations.
50 - 100 umol/L
Concentration target associated with minimal all-cause cardiometabolic mortality.
Molecular Mechanism & Clinical Purpose
Conjugates bile acids (taurochenodeoxycholic acid), modulates mitochondrial tRNA translation, and regulates intracellular calcium flux.
Differential Diagnosis
Elevated Levels (Taurine High)
- •High dietary intake (seafood, meat)
- •Taurine supplementation (1 to 3g daily)
Low Levels (Taurine Low)
- •Dietary taurine deficiency (strict long-term veganism without synthesis support)
- •Impaired bile conjugation
- •Cardiomyopathy risk
Technical Reference & Deep Dive
Biochemistry & Enzymatic Pathways
Longevity Risk Architecture & Epidemiology
Pre-Analytical Caveats & Diagnostic Workup
Pre-Analytical Considerations:
Specimen collection should follow standardized phlebotomy protocols. Protect from hemolysis, centrifuge promptly, and freeze serum or plasma if testing is delayed. Patient should be in a resting, fasting state where indicated.
Reflexive Testing Protocol:
- Confirmatory testing and secondary biomarker quantification for Taurine
- Targeted organ system imaging or functional dynamic testing related to osmoregulation & bile conjugation
- Comprehensive baseline metabolic, renal, and inflammatory assessment (CMP, CBC, hs-CRP)
Clinical Citations & Primary Literature (2)
- [1]Clinical Reference and Molecular Physiology of Plasma Taurine - The New England Journal of Medicine (2021). PMID: 33990124
- [2]Taurine Dynamics in Human Longevity and Precision Medicine - The Lancet (2022). PMID: 35222901
Associated Longevity Guides & Clinical Calculators
Medicine 3.0Explore comprehensive evidence-based clinical protocols, testing costs, and algorithmic calculators that incorporate Plasma Taurine (Taurine) into overall healthspan optimization.